Identification of Bt toxin targets in codling moth larvae
Author: Stephen F. Garczynski, Laura Lavine
Published: 2007
Summary: The specific objectives of this proposal include: 1) Determine the potencies of 10 Bt toxins against codling moth larvae and cell line. 2) Determine the mode of action of the most potent Bt toxins. 3) Identify key molecules affected by the bioactive Bt toxins 4) Clone transcripts encoding the key molecules affected by Bt toxins 5) Develop a cell-based assay system to search for novel insecticides that alter key molecules affected by Bt toxins